September 27, 2016

Diabetes Medication

To control my diabetes, I take METFORMIN.  Metformin has been around since the 1950s and is one of the first line of drugs to control Type 2.  It works by controlling the amount of glucose released by the liver.  Some people react adversely to METFORMIN, but I have been lucky and it has kept my hemoglobin A1C levels within range.

When I started taking METFORMIN over 10 years ago, the dosage was 500 mg once a day.  Every 3 to 5 years, the dosage increased.  First, 500 mg in the morning and 500 mg in the evening.  Now, I am taking 1000 mg in the morning and 1000 mg in the evening.

New Diabetes Medicines

Almost a year ago, my A1C level rose to 7.2.  This was a concern for it indicated that I am developing a resistance to METFORMIN.   My doctor started me on a regimen that included a family of drugs called DPP-4 (dipeptidyl-peptidase 4) inhibitors. These drugs work by increasing the hormones that stimulate the pancreas to produce more insulin and liver to produce less glucose.

He asked me to try the different medicines: JANUVIA, ONGLYZA, TRAJENTA, JANUMET, KOMBIGLYZA, and JENTADUETO in addition to my METFORMIN.  (The last three drugs contain various levels of METFORMIN). Unlike METFORMIN, which costs less than $5 for a 90-day prescription with my insurance company, the new drugs cost from $250 to $300.

I just had a blood test and have an appointment to see my doctor in the next two weeks. Stay tuned!